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Heart and Soul—er… Lungs: New Research on Asthma and Cardiovascular Disease Risk

Alerts have been pinging at me from multiple sources about the link between asthma and cardiovascular disease risk (we’re talking heart attack and stroke, primarily). If you’ve been seeing these articles around the web, too, here’s what’s going on.

A recent study on asthma and cardiovascular disease

Researchers have recently released research stating that adults with “late-onset asthma” 1,2—in this case, a diagnosis of asthma in adulthood, at age 18 or older 1,2—are at 1.6 times the risk of developing cardiovascular disease than those without asthma 1,2.

This is after adjusting for other things that we know of as heart or vascular (veins and arteries) health risk factors. These include demographics such as older age, race, gender, or other health concerns.1,2.

Details on the study

In this study, known as the Wisconsin Sleep Study, which followed a large group of patients from 1989 through 2013. They documented that 13.1% of the randomly chosen participants had asthma. Here’s what they found:1

  • Non-asthmatics had a 10-year cardiovascular disease (CVD) event incidence rate (development of cardiovascular disease) of 8.9%
  • Early-onset asthmatics had a CVD event rate of only 3.8%
  • Late-onset asthmatics (developing asthma after age 18, recall), had a 12.7% CVD event rate—significantly higher than non-asthmatics.

After adjusting for age, sex, and cardiovascular disease risk factors, adults with late-onset asthma are 57% times more likely to experience a cardiovascular (CVD) event compared to those without asthma 1,2.

What does this mean for those with early-onset asthma?

If you, like me, were diagnosed with asthma before age 18, this is probably good news to hear that our CVD risk is the same as someone without asthma—the stats above show lower. However, it’s important to note that the early onset asthmatics only represented 4.3% of the study population, versus 8.8% of individuals with late-onset asthma.1,2

This is why, to my understanding of stats (which I am more than open to be corrected on!), those of us with early-onset asthma appear to have lower risk of cardiovascular disease. Our risk level is essentially the same as those without asthma.

How to monitor your asthma and cardiovascular disease risk

Now, if you’re in the late-onset asthma group, don’t despair. Even though these stats were adjusted for other risk factors, keeping your cardiovascular system healthy still will help you achieve the best results in the long-term. People who eat well, exercise regularly, and keep their lives as low stress as possible are less likely to experience cardiovascular disease. However, those who do and still experience cardiovascular disease may have milder CVD events and/or recover more rapidly than those who don’t.3,4

There is still a lot of research to be done in this area. The article concludes to note that there may be associations with this risk between different asthma phenotypes (a phenotype being “how something manifests” or appears, such as age of onset, allergic or non-allergic, exercise-induced, etc). Hopefully, this is research that we see done in the near future. I’m very interested in the results—and how they might change outcomes for people with late-onset asthma in regard to cardiovascular risk.1,2

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The Asthma.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

  1. Tattersall MC, Barnet JH, Korcarz CE, et al. Late-inset asthma predicts cardiovascular disease events: The Wisconsin sleep cohort. Journal of the American Heart Association. 2016;5(9):1-7. doi: 10.1161/JAHA.116.003448.
  2. Casey T. for Cardiovascular Business. Adults with late-onset asthma may have increased risk of cardiovascular disease events. http://www.cardiovascularbusiness.com/topics/practice-management/adults-late-onset-asthma-may-have-increased-risk-cardiovascular-disease-events. Accessed September 2016.
  3. Science Daily. Higher fitness linked to reduced risk of death after first heart attack. https://www.sciencedaily.com/releases/2016/02/160201084350.htm. Accessed September 2016.
  4. Gallanagh S, Quinn TJ, Alexander J, Walters MR. Physical activity in the prevention and treatment of stroke. ISRN Neurology. 2011;Article ID 953818. doi:10.5402/2011/953818.

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