Singular/Montelukast: Not Just For Asthma – Part 1
Why Montelukast? For asthma and beyond.
Typically, physicians take an “entire airway” or “one airway” approach to asthma management 8, which is why many asthmatics are identified as having co-occurring sinus disease or allergic/non-allergic rhinitis. The thought is that the inflammatory process must be addressed throughout the airway for optimal results from treatment. 8 Allergic rhinitis is one of the approved uses for Singulair, but one you likely don’t hear about very often, as it’s a “second line” treatment. 9 Keeping treatment localized, by way of intranasal corticosteroids (nasal sprays), is preferred to cut down on potential side effects, which explains why—since intranasal steroids are effective and safe—Singulair hasn’t hit the mainstream for rhinitis treatment. However, leukotrienes are also found to be present in those with exercise-induced asthma—montelukast is sometimes prescribed for prophylaxis (prevention) of EIA symptoms (bonus!). 5 In addition, emerging research is looking at the roles of montelukast on Parkinson disease 10, menstrual-related pain 11, and more—so it doesn’t just go beyond asthma in terms of working upward to upper-airways disease in the sinuses!
After learning more about the potential role of montelukast in rhinitis treatment, and based on my lack of “compliance” with my nasal steroids, I figured looking more into this research could be interesting. Now that we’ve got the basics of montelukast down, we’ll tackle that topic in my next post.
Have you tried Singulair (montelukast) for your asthma? Did it work for you?