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Corticosteroid Injections: A Pain In The Butt?

Asthma is a pain in the butt, sometimes. Sure, that’s probably true for asthma in and of itself, but I’m referring to systemic corticosteroid injections. Those of us who have had a systemic corticosteroid injection down there know exactly what I mean.

The initial asthma attack

You make the right decision to visit an emergency room near you. You are probably given a nebulizer breathing treatment, probably with albuterol (even if you have a nebulizer that you already used at home). The attending doctor then decides to give you an injection of a systemic corticosteroid before you go home.

You probably already know what this is, and why it’s needed. The most common systemic corticosteroid used in emergency rooms where I live is methylprednisolone (Solu-Medrol). It can be given in your IV, if you have one. It used to be that all asthmatics would get IVs. The old thinking is we needed to be hydrated.

But, more often than not, we asthmatics don’t get IVs anymore. And, if that’s the case, and the attending physician decides you would benefit from some systemic steroids to end your flare-up and control your asthma…

Location of the injection

Yep, the good old gluteus maximus. It’s a good sting, surely enough. But the worst part is it causes a dull pain that lasts for several hours, maybe even a few days, after the injection. For some reason, steroid injections do that.

Again, this is nothing we asthmatics can’t deal with. It’s, as my mom would say, a good sort of pain. It’s good, sort of like feeling sore the day after a good workout. As mom said, it means you are making progress. In our case, the progress is the inflammation in your lungs will go down, helping you breathe easier.

Corticosteroids, more often called simply steroids, reduce the immune response that causes airway inflammation. When you are exposed to your asthma triggers, this inflammation may worsen, and this is what causes asthma symptoms.

Inhaled corticosteroids (ICS) usually help to lessen this inflammation. So, if you are already taking an ICS every day, and you end up in the ER, you might be thinking: Why do I still need to use systemic steroids?

Well, the answer is that, while ICS reduces airway inflammation to control asthma, sometimes, when we are exposed to one of our triggers (such as a respiratory virus), the ICS is not enough. You see, ICS contains a very low dose of steroids. Sometimes our lungs need a boost. When our doctors think this is the case, we get an injection of systemic ICS.

Effects of the injection

Your doctor decided, that to help you get over your asthma attack, a steroid injection is necessary. If you already have an IV, you will probably not even feel it. However, if you don’t, the medicine must be injected into a muscle. The most common injection points are the deltoid muscles (the side of your shoulder) or your gluteus maximus (your butt).

I have no idea how a nurse will decide which spot is best. But, quite often, it’s in the butt. And, this reminds me of a story.

There was one time when I was, I think, 21 years old. I was having a pretty bad asthma attack, and decided I could just drive myself to the emergency room. I did. Among other things, I was given a steroid shot in the left butt cheek.

Injections are painful

But, worse than the initial sting, was that the injection site hurt like crazy.

The nurse didn’t want me to drive home. But not because my butt cheek hurt, more so because I was given a shot of Sus-phrine (my last one ever before the product was discontinued), and a couple Ventolin breathing treatments. (This was actually the day I was introduced to Ventolin solution. Before this time I was using Alupent).

But, she did allow me to go home. On the way, however, my butt hurt so bad I actually had to, sort of, stand with my butt cheek off the seat. It was hard to drive this way, but I managed.

I know it’s not just me, as I have had many, many, many asthma patients over the years confirm this for me after they were given their shot by various nurses.

And it has nothing to do with the nurses technique, in my opinion. Steroid shots just hurt. They are a pain in the butt, or arm if you got the shot there.

Recommended site of injection: arm.

You don’t have to sit on your arm.

It was after this ER visit that I decided I would never drive myself to the ER again. And I never have. I have been to the ER, but have never driven myself since that day.

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.


  • BnNQ
    1 year ago

    I always have issues with my asthma and it took me twenty years before I ended up with a shot in my butt…I’m telling you I hate shots but it didn’t hurt getting it just after was a bit tender Haha!

  • Leon Lebowitz, RRT moderator
    1 year ago

    Hi BnNQ and thanks for your post. I remember that well. So many years ago, the family doctor used to come to the house (when I was a kid), and give me the epinephrine injection in my butt as well. It hurt like hell, but I didn’t care – I could breathe again!! Leon (site moderator)

  • PsoriaticAsthmatic
    2 years ago

    SO much yes, the only shot I’ve had that is worse is when I took Humira for my arthritis.

  • John Bottrell, RRT moderator author
    2 years ago

    Good medicine. Bad ouch! John. Site Moderator

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