Why No OTC Asthma Inhalers?

So, they say asthma medicines save lives. They say side effects are negligible. So, why do I need a prescription to get one? Why aren’t they available over the counter (OTC)? These are great questions. And I have good answers. Allow me to explain.

Some history of asthma treatments

To get our answers we have to travel back to 1956. This was a great year for asthmatics. That was the year the inhaler was invented. The first inhaler medicine was epinephrine. The second was isoproterenol. A year later, in 1957, they entered the market. These were the first two asthma rescue inhalers. They were called the Medihaler Epi and Medihaler Iso.

As you can imagine, this was a huge boon for asthmatics. This was not the first time asthmatics had access to rescue medicine. But, it was the first time it was available in small, portable devices. They could be stuffed in pockets and purses. They could be used anywhere, anyplace, and anytime. It was such an awesome invention.

But, there was a surge in asthma-related deaths. Doctors were made aware of these statistics. This resulted in a subsequent decline in rescue inhaler prescriptions.

There were various studies attempting to explain this. No conclusive answers were discovered. But, there were theories postulated.

One theory blamed the inhalers. Epinephrine opens airways to make breathing easier. But, it also has a strong cardiac effect. So, the theory said side effects of these inhalers were too strong for some asthmatics. This caused their deaths.

Another theory blamed the deaths on poor education. This is the theory I like best. It postulated that asthmatics were over-relying on their inhalers. They were using them too much. They puffed and puffed and puffed. They figured they could treat their asthma attacks on their own, rather than seeking help. By the time they finally sought help it was too late.

So, this inspired a major educational campaign. Doctors were educated about these inhalers. Doctors were taught to educate patients, rather than deny them inhalers that could save their lives.

Patients were instructed to only use them as instructed. If they used them more than prescribed, they were to seek help. In this way, an increase in inhaler use was seen as a sign of poor asthma control.

This seemed to help quite a bit. These inhalers were soon available over the counter (OTC). Surely this was a good idea. It made the inhalers easier to get. It made them cheaper.

The epinephrine inhaler stayed on the market until 2011. It stayed on the market not because it was considered safe. It stayed on the market because it was grandfathered in. By this time, however, it was a generic inhaler. It was called Primatene Mist.

Now, let’s put the epinephrine inhaler aside.

Researchers continued working with the epinephrine molecule. In the 1960s they came up with a stronger rescue medicine called metaproterenol (Alupent). It still had some cardiac effects. But, it was much safer than the old epinephrine inhalers. During the  1970s and 1980s, Alupent was the most prescribed asthma rescue medicine.

In 1984, Alupent was considered very safe. So, it was introduced as an OTC medicine. Again, it was decided this would make the medicine easier to get. It would make it cheaper. I know, because I loved this. I needed one and didn’t have to tell mom. I didn’t need to see my doctor. I walked into a pharmacy and bought one with cash.

But, again, there was a surge in asthma-related deaths. I read the stories in the evening newspaper. If I remember right, there were seven deaths blamed on the inhalers in a short time.

The same two theories mentioned above were discussed again. Rather than mess around, the FDA quickly decided to make Alupent a prescription medicine again. It was no longer available OTC.

This was a little frustrating for asthmatics like me. But, in retrospect, I think they made a smart decision. Yes, it’s nice to have easy access to rescue medicine. Yes, it makes them cheaper. But, as history shows, what’s easiest and cheapest is not always what’s best for asthmatics.

And now you know why.

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The Asthma.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

Comments

View Comments (4)
  • attila
    3 months ago

    The real reason is that everyone in the med biz is in bed with each other. Docs love visits, that is the way they bill. So of course they want you in the office to prescribe. Insurance companies and clinics/hospitals cut deals for billing purposes-reduced charges for net 30-the sooner the insurance pays the clinic-the lower the procedural price…you get the money to me faster and I will give you a “discount”…if you don’t need insurance-Cigna-Aetna-lose out…and of course the I imagine the makers of prescription inhalers were banging the drums to get rid of $12 OTC inhalers…all of you in medicine are scheming bastards…that is why..

  • John Bottrell, RRT moderator author
    3 months ago

    Guess I can’t argue with you too much there. Not sure if that’s the actual intent, but I can see why the suspicion would arise. John. Site Moderator.

  • idigbones
    6 months ago

    Except I can’t afford the medicines. I think I would rather take my chances with the OTC meds. At least I could breath. Medicines can’t save lives if it’s not affordable.

  • Leon Lebowitz, RRT moderator
    6 months ago

    We hear you, idigbones, and sympathize. It’s clear that medications can be expensive, even with the various third party payers. If there is anything we can assist you with, please let me or any other moderator/team member know. What are you doing now to manage your condition? Warmly, Leon (site moderator)

  • Poll