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Undiagnosed childhood asthma = hardened bronchial tubes

Hi, I'm new to this forum and am hoping there's someone else out there that might have some suggestions for what I am dealing with.
My pulmonologist thinks that I had childhood asthma that went undetected which has led to hardened bronchial tubes.
The result is that no inhalers seem to help (irreversible I think he called it).
I am on Trilegy, QVar and Montelukast and have also been injecting Dupixent for the past 2 ears. I have not seen any improvement in my lung function tests so I have my doubts that there will ever be any improvement.
Does anyone else have this irreversible type of asthma? Did anything work?
The other major issue I have is the constant throat clearing. It happens every day for pretty well the entire time I am awake. I feel sorry for people in the office next to me as they have to hear it continuously!
Has anyone ever found anything that helps in this regard?


  1. Hi - welcome! You may be aware we cannot provide medical advice or diagnostics over the internet (for your own safety), but your concern certainly warrants a reply.
    To me, this sounds like a real dilemma! My initial thought is that perhaps this was not asthma. Without any other medical history, it's hard to determine. However, it is not clear (to me) what the pulmonologist means by 'hardened bronchial tubes'. Some folks refer to that part of the pulmonary anatomy as bronchioles or, the conducting airways of the pulmonary system. If, as he suggests, these are 'hardened' it may in fact be termed a restrictive lung disease. Asthma. as you may know, is an obstructive lung disease. As well, asthma is considered to be a reversible lung disease. This means that the symptoms can be reversed with proper treatment leaving no permanent lung damage (as with chronic obstructive pulmonary disease (COPD)). If what you have is not reversible (with treatment), you may have another diagnosis. From my own perspective, this is not a simple issue as yet. What will make this more understandable and, subsequently identifiable, would be a definitive diagnosis. That is what seems to be missing now.
    What do you think?
    Leon L (author/moderator

    1. Ny doctor prescribed glutathione for my nebulizer and peroxide. Persistent use helped me

      1. Hi Swillet - thanks for your post. This is a good time to remind our community members not to try anything new (either prescribed or over-the-counter), without speaking with one's physician first.
        I can also tell you the medical literature addresses the concern about using hydrogen peroxide for nebulization. I would like to share this one reference example from the Asthma and Allergy Foundation of America (AAFA): I do hope our readers find this to be helpful.
        Wishing you well,
        Leon L (author/moderator

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