Hi rose, and Happy New Year to you as well!
I know we have had conversations here within the community in the past and I am glad to see you engaging here again!
You may be aware we cannot provide medical advice or diagnostics over the internet (for your own safety), but your concern certainly warrants a reply.
Generally speaking, it is suggested that folks use the rescue medication (whether it is a metered dose inhaler (MDI), or medication nebulizer therapy), prior to using inhaled corticosteroids (ICS) therapy. Sometimes and usually, the prescribing physician provides these types of instructions for the patient when the medications are prescribed.
Since you are just starting the Trelegy and adding it to your medication regimen, you may want to wait until you can contact your physician directly. That would be the safest and most prudent course to follow.
What do you think?
Leon (site moderator asthma.net)