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Xolair—Any developing side effects after longterm use?

Specifically, would 15+ years of Xolair once a month result in any skin issues? I know it is used for Urticarial vasculitis (which I have) and many are helped, but it did not help my skin (it helped asthma and rhinitis, however). Lots of UV flares lately. Can Xolair hurt my skin?

  1. Hi ,

    We do have an article that goes in-depth about Xolair and the potential side effects. One side effect does include a skin rash. If you'd like to read more about this, you may do so here: https://asthma.net/treatment/xolair/ There has been some research done on asthma and skin conditions, one being hives. However, hives typically respond well to Xolair. You may read more about the connection here: https://asthma.net/living/hives-urticaria/

    Unfortunately, we are unable to offer medical advice, so this may be a great question to ask your doctor! Have you met with your doctor about this?

    Warmly,
    Sidney

    1. I'm also looking for info on Xolair because my respiratory consultant offered it to me last week.


      1. Hi Sunnyday, and thanks for your post.
        We actually have a good reference article published (right here on our asthma.net community website), which focuses on this method of treatment (Xolair).
        I see my colleague, , posted it in her reply above to .
        Perhaps you did not see it as yet.
        For your convenience, here is a link to that article: https://asthma.net/treatment/xolair.
        I do hope this provides you with the information you are interested in.
        Wishing you well,
        Leon (site moderator asthma.net)

    2. Hi Leon


      Thank you for your very helpful reply! I'm going to look at those articles now.


      Best wishes!

      1. It's our pleasure, Sunnyday. I do hope you find the information is helpful to you as you decide, with your physician, whether to use the medication, Xolair, moving forward.
        Please do check back and keep us apprised of your progress.
        All the best,
        Leon (site moderator asthma.net)

    3. Hi Leon


      I do think it will be the right medication because the hospital is aiming to get me off steroids (at least steroid asthma treatment; I might need Hydrocortisone though due to the adrenal insufficiency the Fluticasone has caused).


      My asthma is mostly allergic, so my consultant has started me now on Montelukast, then when my Seretide is lower, it'll be time for Xolair.


      Does this forum have people who got adrenal insufficiency and pituitary ACTH suppression from asthma inhalers? That's my problem, and it'd be great to hear their experience of tapering off the steroid inhaler. So few doctors seem to know that inhalers can act systemically (I am in the UK).







      1. I did some research on our community site and found a link to several articles referring to your question above. Reviewing these articles may help you.

        https://asthma.net/search?s=adrenal%20insufficiency%20and%20pituitary%20ACTH%20suppression%20from%20asthma%20inhalers

        Wishing you the best in health and wellness - Rebecca (comm advc)


      2. Hi again, Sunnyday, and thanks for your response and further explanation. Like you, I'm hopeful the planned medication regimen you are working on with your medical team proves to be effective for you.
        As for you inquiry regarding the adrenal and pituitary relationship to the use of metered dose inhalers (MDI's), I see my colleague, , has provided links to some articles she felt may be of help to you. I do hope you have an opportunity to look over the material and possibly get back to her with your impression.
        Wishing you well,
        Leon (site moderator asthma.net)

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