I have severe persistent asthma and have tried every inhaler in my doctor’s chart. Some have worked better than others. The latest was Breztri and it worked but not always. So after 4 different providers recommended I switch to an nebulizer combination of Budesonide Arformoterol and lately Yuperli I am giving it a try. So far I am coughing less and needing less Albuterol. It does take longer and it is not as portable as the inhaler but if it works I’ll keep doing it. We’ll see what happens when fall comes.